HORDB

ID: hor001152
Uniprot ID: P41854
Protein name: Neuropeptide AF3
Gene name: AFP-1
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: ENEKKAVPGVLRF
Length: 13
Propeptide: MVELAAIAVHLFAILCISVSAEIELPDKRAQFDDSFLPYYPSSAFMDSDEAIVAVPSSKPGRYYFDQVGLDAENAMSAREKRGFGDEMSMPGVLRFGKRGMPGVLRFGKRENEKKAVPGVLRFGKRGDVPGVLRFGKRSDMPGVLRFGKRSMPGVLRFGRR
Signal peptide: MVELAAIAVHLFAILCISVSA
Modification: T13 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001152_AF2.pdb

hor001152_ESM.pdb

Mass:	170095	Formula:	C67H111N19O19
Absent amino acids:	CDHIMQSTWY	Common amino acids:	EKV
pI:	9.53	Basic residues:	3
Polar residues:	2	Hydrophobic residues:	5
Hydrophobicity:	-61.54	Boman Index:	-2755
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	82.31
Instability Index:	3886.15	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 21524146
Title: Discovery of Neuropeptides in the Nematode Ascaris Suum by Database Mining and Tandem Mass Spectrometry